Estraclear (120 Capsules)
Estraclear represents a three-dimensional approach to supporting healthy estrogen metabolism. Research suggests that diindolylmethane (DIM), curcumin (from turmeric extract), and the patented black pepper extract BioPerine® support balanced estrogen metabolism.
DIM (3,3’-diindolylmethane) is the stable, bioactive metabolite formed when stomach acid breaks down indole-3-carbinol (I3C), a sulfur-containing glucosinolate present in cruciferous vegetables. DIM has been found to support hormone metabolism and immune activity, and stimulate antioxidant and detoxification systems. Curcumin and BioPerine® provide complementary support for DIM’s role in healthy cell function.
Support of Hormone Metabolism: Healthy metabolism of exogenous and endogenous estrogens can be pivotal for hormonal balance. DIM has been studied for its role in supporting prostate health as well, by reducing dihydrotestosterone binding to androgen receptors.
Support of Cell Function and Metabolism: Orchestration of metabolism by the thyroid gland is dependent on hormone balance. DIM was found to target proteolytic enzymes (MMP-2 and MMP-9), thus supporting the normal function and activity of thyroid cells in
vitro. Ongoing research reveals DIM’s positive role in regulation of gene expression, protein production, and cell function. Downregulation of certain proteins (survivin, Bcl-2, and cdc25A) and upregulation of protective proteins (NRF2 and cyclin-dependent kinase inhibitor p21waf1) promoted healthy cell growth.
Antioxidant and Detoxification Support: Estraclear provides support for both antioxidant and detoxification systems which, in turn, support cellular function and integrity. Antioxidant activity is crucial to counteracting oxidative molecules normally produced during phase I detoxification. Research on DIM suggests that it plays an important role in activating detoxification enzymes in human hepatocytes, further supporting biotransformation at a primary site in the body.
Curcumin as the major curcuminoid found in turmeric, curcumin is valued for its promotion of antioxidant activity, support of metabolic detoxification, and modulation of cytokine production.
BioPerine is a patented form of piperine, the main alkaloid from black and long pepper plants that has been found to effectively support the absorption of nutrients.
2 Capsules Contain:
Turmeric Extract (Curcuma longa)(rhizome)(95% curcuminoids).....................250 mg
DIM (diindolylmethane)........................................................................................150 mg
Black Pepper Extract (Piper nigrum)(fruit)(BioPerine®).....................................2.5 mg
HPMC (capsule), stearic acid, magnesium stearate, microcrystalline cellulose, silica, and medium-chain triglyceride oil.
BioPerine is a registered trademark of Sabinsa Corp. BioPerine isprotected by US patents 5,536,506; 5,744,161; 5,972,382; and 6,054,585.
Take two capsules daily, or as directed by your healthcare practitioner.
Does not contain: Wheat, gluten, corn, yeast, soy, animal or dairy products, fish, shellfish, peanuts, tree nuts, egg, ingredients derived from genetically modified organisms (GMOs), artificial colors, artificial sweeteners, or artificial preservatives.
Consult your healthcare practitioner prior to use. Individuals taking medication, especially blood thinners or cancer treatment, should discuss potential interactions with their healthcare practitioner.
Store in a cool, dry place (59°F-85°F) away from direct light. Keep out of reach of children.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.